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Post Exposure Prophylaxis (PEP)


What can I do if I've potentially been exposed to HIV?
You can  take PEP to kill HIV before it has a chance to cause infection.

What is PEP?
PEP (post exposure prophylaxis) is a procedure to prevent HIV infection in the event of a risky exposure to HIV. PEP involves taking medications that kill HIV before it has a chance to cause infection.

  • PEP is only for people who were just exposed to HIV and do not already have it.
  • PEP combines three HIV drugs (pills) that you take for four weeks. Some HIV drugs may not be safe for pregnant women.  Tell the health care worker if you may be pregnant so that they know which drugs to give you.

Does PEP work?
While PEP has not been proven to work for all high-risk exposures, evidence from studies demonstrates that PEP, when given in a timely manner, can dramatically reduce the risk of HIV infection.

When do I start PEP?
If you have been exposed to HIV, go to an emergency room or clinic RIGHT AWAY. See locations below.

You should start PEP within two hours of your exposure and generally preferred no later than 36 hours. 72 hours from possible exposure is the maximum period of time for which PEP can be offered.

What should I know before I start PEP?
When you go to the hospital or clinic, you will be asked to have an HIV test. Taking an HIV test at this time will let you and your health care worker know if you already have HIV.  You may be eligible for support provided by the New York City Department of Health for services provided through our outpatient program.

Where can you access PEP?
Mount Sinai Hospital
PEP is offered 24 hours a day, seven days a week through Mount Sinai Hospital’s Emergency Department and outpatient program. For evening and weekend services, the Emergency Department is located on 101st Street between Madison and Fifth Avenues. For services during regular business hours, the outpatient program is housed within two locations:

Comprehensive Health Program Downtown
275 7th Avenue, 12th Floor
New York, NY 10001
(212) 604-1720
Monday, Tuesday, Wednesday, Friday: 9am to 4pm Thursday: 9am—6pm

Jack Martin Practice
17 East 102nd Street, 3rd Floor
New York, NY 10029
(212) 241-0710
Monday—Friday: 9am—4pm

Callen-Lorde Community Health Center
If you have been exposed to HIV in the last 72 hours, please call Callen-Lorde Community Health Center at 212.271.7229 Callen-Lorde Community Health Center  is located at 356 West 18th Street, New York, NY 10011.

To learn more about PEP and HIV and AIDS:
Call the New York State HIV/AIDS Information Line:
1-800-541-AIDS (English) 1-800-233-SIDA (Español)